Ideally, you want to make a static binary, otherwise the dynamic linker pollutes your address space with shared libs right in the middle. (NOTE: actually, this shouldn't matter so much anymore, now that we only allocate huge, fixed-size slabs) Make sure your libevent has epoll (Linux) or kqueue (BSD) support. Using poll or select only is slow, and works for testing, but shouldn't be used for high-traffic memcache installations. To build libevent with epoll on Linux, you need two things. First, you need /usr/include/sys/epoll.h . To get it, you can install the userspace epoll library, epoll-lib. The link to the latest version is buried inside http://www.xmailserver.org/linux-patches/nio-improve.html ; currently it's http://www.xmailserver.org/linux-patches/epoll-lib-0.9.tar.gz . If you're having any trouble building/installing it, you can just copy epoll.h from that tarball to /usr/include/sys as that's the only thing from there that libevent really needs. Secondly, you need to declare syscall numbers of epoll syscalls, so libevent can use them. Put these declarations somewhere inside : #define __NR_epoll_create 254 #define __NR_epoll_ctl 255 #define __NR_epoll_wait 256 After this you should be able to build libevent with epoll support. Once you build/install libevent, you don't need to compile memcache or link it against libevent. Don't forget that for epoll support to actually work at runtime you need to use a kernel with epoll support patch applied, as explained in the README file. BSD users are luckier, and will get kqueue support by default.